ADAR1 Partners, LP5%+ holder2,241,926 sh10.0%
Lynx1 Master Fund LP5%+ holder2,064,230 sh10.0%
Point72 Associates, LLC5%+ holder2,247,997 sh10.0%
Ikarian Healthcare Master Fund LP, Boothbay Absolute Return Strategies, LP and Boothbay Diversified Alpha Master Fund LP5%+ holder1,754,298 sh8.2%
Affinity Healthcare Fund, LP5%+ holder2,248,010 sh10.0%
Cormorant Global Healthcare Master Fund, LP5%+ holder2,248,010 sh10.0%
Adage Capital Partners, L.P.5%+ holder2,248,010 sh10.0%
Vestal Point Master Fund, LP and affiliates5%+ holder2,248,010 sh10.0%
SilverArc Capital Alpha Fund I, LP and affiliates5%+ holder2,248,010 sh10.0%
All current executive officers and directors as a group (9 persons)all directors and officers as a group558,665 sh2.8%