Entities affiliated with Marshall Wace, LLP5%+ holder28,103,699 sh10.0%
Entities affiliated with OrbiMed Advisors LLC5%+ holder27,491,521 sh10.0%
Entities affiliated with Rosalind Advisors, Inc.5%+ holder10,987,105 sh10.0%
Entities affiliated with Nantahala Capital Management, LLC5%+ holder9,671,157 sh10.0%
Soleus Private Equity Fund III, L.P.5%+ holder6,711,630 sh10.0%
Entities affiliated with Velan Capital5%+ holder3,951,756 sh10.0%
Entities affiliated with Aberdeen Group5%+ holder3,173,364 sh6.8%
Entities affiliated with Parkman Healthcare5%+ holder2,440,633 sh5.2%
Marvin Slosmanofficer2,556,760 sh5.2%
Michael Lawlessofficer4,753,265 sh10.1%
All directors and executive officers as a group (10 persons)all directors and officers as a group12,614,397 sh25.0%